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Glossary

Systematic reviews: a protocol first, then a search anyone could repeat

A systematic review answers a defined question by searching the literature according to a protocol registered in advance, screening every hit against stated inclusion criteria, and appraising the studies that survive. The method is documented in enough detail that another team could repeat it and reach the same set of included studies.

Why it matters when you are writing

The protocol is what makes it systematic, and it is written before the searching starts. It fixes the question, the databases, the search strings, the inclusion and exclusion criteria, the screening procedure, and the appraisal instrument. Registering it — PROSPERO in health research, or an open repository elsewhere — creates a public record that the criteria were not adjusted once results started appearing.

Reporting follows a standard. PRISMA asks for a flow diagram accounting for every record: identified, screened, excluded with reasons, included. Journals in health and increasingly in social science will return a manuscript without one. The diagram is tedious to assemble and it is also the part a skeptical reader checks first, because it shows what you threw away.

The honest limitation is time and staffing. A full systematic review typically involves two independent screeners, a conflict-resolution step, and months of work — which is why solo doctoral students are often better served by a well-executed scoping review or a rigorous narrative review, clearly labeled as such. Calling a narrative review “systematic” because you searched several databases is a claim reviewers check.

IN PRACTICE

What the protocol fixes in advance

Question, databases (MEDLINE, Embase, PsycINFO), date range, language limits, study designs eligible, minimum sample size, the appraisal tool, and how two screeners resolve disagreement — all specified before the first search is run.

OFTEN CONFUSED WITH

What Systematic review is not

Literature review
A narrative literature review selects sources by expert judgment; a systematic review follows a protocol that makes selection reproducible.
Meta-analysis
A meta-analysis is the statistical pooling step; many systematic reviews include one, and many report a narrative synthesis instead.
Scoping review
A scoping review maps the extent and nature of the evidence on a broad topic; a systematic review answers one tightly defined question.

Questions about systematic review

Does a systematic review have to include a meta-analysis?

No. If the included studies are too heterogeneous in design, population, or outcome, pooling them would produce a misleading number, and a narrative synthesis is the correct choice.

What is PRISMA?

A reporting standard specifying what a systematic review must disclose, including the flow diagram accounting for every record from identification to inclusion.

Can one person conduct a systematic review?

It is done, but independent double screening is the expected standard and single-screener reviews are commonly criticized in peer review. Plan for a second screener.

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